Daniela Vullo Selected Research

Protein Isoforms (Isoforms)

1/2022	New Pyridinium Salt Derivatives of 2-(Hydrazinocarbonyl)-3-phenyl-1H-indole-5- sulfonamide as Selective Inhibitors of Tumour-Related Human Carbonic Anhydrase Isoforms IX and XII.
5/2020	Discovery of New 1,1'-Biphenyl-4-sulfonamides as Selective Subnanomolar Human Carbonic Anhydrase II Inhibitors.
1/2019	SLC-0111 enaminone analogs, 3/4-(3-aryl-3-oxopropenyl) aminobenzenesulfonamides, as novel selective subnanomolar inhibitors of the tumor-associated carbonic anhydrase isoform IX.
1/2018	Novel sulfonamide incorporating piperazine, aminoalcohol and 1,3,5-triazine structural motifs with carbonic anhydrase I, II and IX inhibitory action.
12/2017	Potent and Selective Carboxylic Acid Inhibitors of Tumor-Associated Carbonic Anhydrases IX and XII.
1/2017	Coumarins and other fused bicyclic heterocycles with selective tumor-associated carbonic anhydrase isoforms inhibitory activity.
1/2017	Synthesis and carbonic anhydrase inhibition of a series of SLC-0111 analogs.
1/2017	5-Substituted-benzylsulfanyl-thiophene-2-sulfonamides with effective carbonic anhydrase inhibitory activity: Solution and crystallographic investigations.
1/2017	Synthesis of new 3-(2-mercapto-4-oxo-4H-quinazolin-3-yl)-benzenesulfonamides with strong inhibition properties against the tumor associated carbonic anhydrases IX and XII.
1/2017	N-Substituted and ring opened saccharin derivatives selectively inhibit transmembrane, tumor-associated carbonic anhydrases IX and XII.

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Daniela Vullo Research Topics

Disease

102	Neoplasms (Cancer) 12/2022 - 03/2003
9	Glaucoma 05/2020 - 02/2002
8	Dandruff 05/2019 - 04/2012
6	Neoplasm Metastasis (Metastasis) 01/2019 - 03/2011
5	Malaria 12/2018 - 09/2014
5	Melioidosis 12/2018 - 01/2017
5	Hypoxia (Hypoxemia) 01/2018 - 07/2010
4	Obesity 11/2019 - 02/2004
4	Infections 12/2016 - 02/2014
4	Alzheimer Disease (Alzheimer's Disease) 01/2016 - 05/2006
4	Carcinogenesis 10/2014 - 11/2005
4	Periodontitis 09/2014 - 07/2013
3	Rheumatoid Arthritis 01/2019 - 01/2017
3	Dehydration (Water Stress) 10/2016 - 11/2010
3	Epilepsy (Aura) 05/2009 - 08/2007
2	Tularemia 01/2017 - 01/2017
2	Seizures (Absence Seizure) 01/2016 - 05/2009
2	Disease Progression 02/2004 - 03/2003
1	Cholera 12/2019
1	Seborrheic Dermatitis 05/2019
1	Ataxia Telangiectasia (Louis Bar Syndrome) 02/2017
1	Bacterial Infections (Bacterial Infection) 01/2017
1	Amnesia (Dissociative Amnesia) 01/2017
1	Melanoma (Melanoma, Malignant) 12/2016
1	Mycoses (Diseases, Fungus) 12/2016
1	Cognitive Dysfunction 01/2016
1	Intellectual Disability (Idiocy) 01/2016
1	Carcinoma (Carcinomatosis) 01/2016
1	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2016
1	Nervous System Diseases (Neurological Disorders) 12/2015
1	Ascariasis 09/2015

Drug/Important Bio-Agent (IBA)

97	Carbonic Anhydrases (Carbonic Anhydrase)IBA 12/2022 - 05/2003
62	IsoenzymesIBA 12/2016 - 02/2002
61	Protein Isoforms (Isoforms)IBA 01/2022 - 08/2003
54	SulfonamidesIBA 02/2017 - 03/2003
40	EnzymesIBA 05/2019 - 05/2003
23	Carbonic Anhydrase InhibitorsIBA 01/2019 - 03/2003
15	ZincIBA 10/2014 - 05/2003
14	Pharmaceutical PreparationsIBA 10/2020 - 04/2006
13	Carbonic Anhydrase IXIBA 02/2017 - 03/2003
11	BenzenesulfonamidesIBA 12/2019 - 03/2007
11	AnionsIBA 12/2018 - 10/2003
9	Acetazolamide (Diamox)FDA LinkGeneric 10/2020 - 03/2003
6	sulfamic acid (ammonium sulfamate)IBA 02/2017 - 12/2003
6	Proteins (Proteins, Gene)FDA Link 02/2017 - 03/2005
5	Amino Acids FDA Link 12/2018 - 08/2007
5	AminesIBA 12/2018 - 08/2007
5	Sulfanilamide FDA Link 01/2017 - 02/2004
4	Anti-Bacterial Agents (Antibiotics)IBA 01/2017 - 02/2014
4	dorzolamide (Trusopt)FDA LinkGeneric 05/2015 - 03/2003
4	CarbohydratesIBA 10/2014 - 04/2007
3	CoumarinsIBA 01/2017 - 11/2014
3	Hydro-Lyases (Dehydratases)IBA 01/2016 - 01/2007
2	SLC-0111IBA 01/2019 - 01/2017
2	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 01/2018 - 01/2017
2	dipotassium trioxohydroxytetrafluorotriborateIBA 12/2016 - 04/2015
2	LigandsIBA 03/2016 - 04/2014
2	isoquinolineIBA 01/2016 - 03/2010
2	Biological ProductsIBA 12/2013 - 05/2011
2	Anticonvulsants (Antiepileptic Drugs)IBA 04/2012 - 05/2009
2	Phenol (Carbolic Acid)FDA Link 03/2011 - 10/2009
2	GlycoconjugatesIBA 03/2008 - 04/2007
2	SugarsIBA 03/2008 - 05/2003
2	Protons (Proton)IBA 01/2007 - 09/2006
2	Methazolamide FDA LinkGeneric 05/2003 - 03/2003
2	Ethoxzolamide (Ethamide)FDA Link 05/2003 - 03/2003
2	brinzolamide (Azopt)FDA Link 05/2003 - 03/2003
1	Monoclonal AntibodiesIBA 12/2022
1	Carbon MonoxideIBA 01/2019
1	Carboxylic AcidsIBA 12/2017
1	3-nitrobenzoic acidIBA 12/2017
1	BiguanidesIBA 02/2017
1	Tirapazamine (SR 4233)IBA 02/2017
1	Chlorambucil (Leukeran)FDA Link 02/2017
1	Phenformin (Fenformin)IBA 02/2017
1	Temozolomide (Temodar)FDA LinkGeneric 02/2017
1	Sulindac (Copal)FDA LinkGeneric 01/2017
1	Cyclooxygenase InhibitorsIBA 01/2017
1	SaccharinIBA 01/2017
1	Phenylalanine (L-Phenylalanine)FDA Link 01/2017
1	Diclofenac (SR 38)FDA LinkGeneric 01/2017
1	benzamideIBA 01/2017
1	Enzyme Inhibitors (Inhibitors, Enzyme)IBA 01/2017
1	KetorolacIBA 01/2017
1	Ketoprofen (Orudis)FDA LinkGeneric 01/2017
1	Ibuprofen (Motrin)FDA LinkGeneric 01/2017
1	Indomethacin (Indometacin)FDA LinkGeneric 01/2017
1	Insulin-Like PeptidesIBA 12/2016
1	Telomerase (Telomerase Reverse Transcriptase)IBA 12/2016
1	BoronIBA 12/2016
1	Insulin-Like Growth Factor I (IGF-1)IBA 12/2016
1	Volatile Oils (Essential Oils)IBA 07/2016
1	CosmeticsIBA 01/2016
1	PolymersIBA 01/2016
1	Nitric Oxide Synthase Type I (Neuronal Nitric Oxide Synthase)IBA 01/2016
1	Antimalarials (Antimalarial Agents)IBA 01/2016
1	Anti-Obesity Agents (Antiobesity Drugs)IBA 12/2015

Therapy/Procedure

15	Therapeutics 12/2017 - 08/2003
4	Drug Therapy (Chemotherapy) 03/2011 - 05/2003
1	Aftercare (After-Treatment) 12/2016